Pemetrexed Continuation Maintenance versus Conventional Platinum-Based Doublet Chemotherapy in EGFR-Negative Lung Adenocarcinoma: Retrospective Analysis.

Tuberc Respir Dis (Seoul) · 2018 · PMC5874144 · PMID 29527843

Europe PMC DOI

hedged sentences

0.0030

closest p · 0.1× alpha

0.0980

boldest claim

The sentences

showed a trendp=0.003actually significant

Univariate analysis revealed that female gender, young age, and no smoking history showed a trend to association with better OS, and good performance status (21.6 months vs. 16.9 months, p=0.003), less advanced stage (19.1 months vs. 13.2 months, p=0.041), and receiving second-line treatment (20.5 months vs. 15.1 months, p=0.049) were significantly associated with better OS.

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an increasing trendp=0.098so close (0.05 < p ≤ 0.1)

Median overall survival showed an increasing trend in the pemetrexed maintenance group (22.3 months vs. 16.1 months, p=0.098).

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