Nuclear Insulin-Like Growth Factor Binding Protein-3 As a Biomarker in Triple-Negative Breast Cancer Xenograft Tumors: Effect of Targeted Therapy and Comparison With Chemotherapy.

Front Endocrinol (Lausanne) · 2018 · PMC5874320 · PMID 29623068

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showed a trendno p-value reported

In an IHC study of breast cancer tissue sections, in which high IGFBP-3 staining showed a trend (non-significant) of association with worse patient survival, “no clear evidence” of nuclear IGFBP-3 staining was reported ( 42 ).

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