Barely Significant
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Widespread domain-like perturbations of DNA methylation in whole blood of Down syndrome neonates.

PLoS One · 2018 · PMC5877863 · PMID 29601581

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showed a trendno p-value reported
The frequencies of hypo- and hypermethylation of all probes about the total number of analyzed probes per chromosome showed a trend towards general hypermethylation in DS vs. controls.

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