Ozanimod (RPC1063), a selective S1PR1 and S1PR5 modulator, reduces chronic inflammation and alleviates kidney pathology in murine systemic lupus erythematosus.

Although we did not observe statistically significant changes in the amount of IFNAR1 on the cell surface of pDCs from mice treated with RP-101075, we did see a numerical trend toward reduced IFNAR1 expression.

also in 1,012 other papers

Of those pDCs still expressing IFNAR1 following RP-101075 treatment, there was also less IFNAR1 on the cell surface, but again, this did not reach statistical significance ( Fig 8B ).

also in 111,027 other papers