Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis.

J Exp Clin Cancer Res · 2018 · PMC5883315 · PMID 29615080

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Kaplan–Meier analysis of the TCGA data, with patients divided into high- or low-HMGB1 groups, showed a trend of lower survival, metastasis-free survival, and high local recurrence associated with high HMGB1 expression (Fig. 6c ).

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