Anti-TNF and thiopurine therapy in pregnant IBD patients does not significantly alter a panel of B-cell and T-cell subsets in 1-year-old infants.

Clin Transl Gastroenterol · 2018 · PMC5886978 · PMID 29618720

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did not reach statistical significanceno p-value reported

Infants exposed to combination therapy (IFX/ADA + IM) exhibited trends toward fewer CD27 + B cells, switched memory B cells, plasmablasts, interferon gamma (IFNγ)-producing CD4 + and CD8 + T cells, and CCR5 + CD4 + T cells, but these did not reach statistical significance.

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