R6/2 -XJB female mice (p<0.01) tended to be smaller than R6/2 -Veh female mice (p<0.001), but this phenotype did not reach statistical significance ( Fig 5A ).
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XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent.
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