Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease.

SKAT required 15FC × 10FNC to report nominally significant p -values, GSKAT required 20FC × 5FNC to report statistically significant p -values, FarVAT-CALPHA did not generate significant p -values unless we used the BLUP correction; FarVAT SKATO reported p -values that were significant at 15FC × 10FNC, and at 5FC × 20FNC if we used the BLUP correction.

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