Meta-analysis of CDKN2A methylation to find its role in prostate cancer development and progression, and also to find the effect of CDKN2A expression on disease-free survival (PRISMA).

Medicine (Baltimore) · 2018 · PMC5895353 · PMID 29561434

Europe PMC DOI

hedged sentence

0.0670

closest p · 1.3× alpha

0.0670

boldest claim

The sentences

showed a trendP = .067so close (0.05 < p ≤ 0.1)

3.3 Subgroup analysis of p16 methylation in PCa versus benign prostatic lesions According to ethnicity (Caucasians and Asians) and testing method (methylation-specific polymerase chain reaction [MSP] and non-MSP), subgroup analysis of ethnicity showed a trend toward the correlation between p16 methylation and Caucasians with PCa (OR = 4.16, 95% CI = 0.91–19.16, P = .067) (Fig. 3 ).

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