Despite the high variability associated with the Ames test, there was a clear trend in the decrease in carcinogens of tobacco smoke after switching to mTHS as compared with those continuing mCC, with a similar trend in the SA group.
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Effects of Switching to the Tobacco Heating System 2.2 Menthol, Smoking Abstinence, or Continued Cigarette Smoking on Biomarkers of Exposure: A Randomized, Controlled, Open-Label, Multicenter Study in Sequential Confinement and Ambulatory Settings (Part 1).
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