A high throughput, functional screen of human Body Mass Index GWAS loci using tissue-specific RNAi Drosophila melanogaster crosses.

PLoS Genet · 2018 · PMC5897035 · PMID 29608557

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0.0860

closest p · 1.7× alpha

0.0860

boldest claim

The sentences

nearly statistically significantP = 0.086so close (0.05 < p ≤ 0.1)

Three of these genes showed highly statistically significant fat mass differences between the KO and WT mice: SETD1A (P = 2.46E-08), TCF7L2 (P = 5.97E-10) and FOXO3 (P = 3.41E-05) while two were nearly statistically significant different from WT: ZNF704 (P = 0.086) and YPEL3 (P = 0.082) and two showed no differences from WT (CLUAP1 and PDK4).

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