Effects of combined tiotropium/olodaterol on inspiratory capacity and exercise endurance in COPD.

Breathing discomfort There was a reduction in breathing discomfort for tiotropium/olodaterol versus placebo as indicated by nominally significant reductions in both the slope and intensity of breathing discomfort at isotime ( figure 5 ), with similar results seen in the individual studies (supplementary table S3 and supplementary figure S8).

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