Engrailed 1 overexpression as a potential prognostic marker in quintuple-negative breast cancer.

Cancer Biol Ther · 2018 · PMC5902237 · PMID 29333926

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borderline significanceno p-value reported

In the analyzed TNBC cohort, nuclear EN1 expression was not significantly associated with a lower OS, while cytoplasmic EN1 expression showed a higher OS rate with borderline significance.

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showed a trendno p-value reported

We confirmed this result by analyzing other cohorts and found that higher EN1 mRNA expression showed a trend towards to association with both a lower and higher OS rate in a TCGA and alternative public microarray dataset, respectively.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.