Altered function and maturation of primary cortical neurons from a 22q11.2 deletion mouse model of schizophrenia.

Transl Psychiatry · 2018 · PMC5904157 · PMID 29666363

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closest p · 1.1× alpha

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boldest claim

The sentences

barely significantp = 0.055so close (0.05 < p ≤ 0.1)

In contrast, Df(16)A +/− neurons showed a barely significant increase in cell capacitance from 40.57 ± 3.07 mV ( n = 28) at DIV7 to 49.38 ± 3.28 mV ( n = 26) at DIV14 ( t test, p = 0.055, Fig. 1c ).

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showed a trendno p-value reported

Notably, unlike mIPSCs, there were no statistically significant differences in the frequency and amplitude of mEPSCs between WT and Df(16)A +/− neurons at both DIV7 and DIV14, although the mutant cells showed a trend of reduced frequency of mEPSCs at both time points (see Fig. 3b,d ).

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