Altered White Matter Integrity in Human Immunodeficiency Virus-Associated Neurocognitive Disorder: A Tract-Based Spatial Statistics Study.

Korean J Radiol · 2018 · PMC5904470 · PMID 29713221

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a decreasing trendno p-value reported

an increasing trendno p-value reported

All the mean FA values showed an increasing trend from the HC group to the HAND group, while the mean MD and RD values showed a decreasing trend ( Fig. 4 ).

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a significant trendno p-value reported

Moreover, most DTI values in tract-specific ROIs showed a significant trend in change starting from the HC group to the HAND group, which suggests that this neural microstructural alteration gradually progresses in HIV-infected patients, a finding also in line with a previously published report ( 36 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.