Cardiovascular effects of sodium glucose cotransporter 2 inhibitors.

Diabetes Metab Syndr Obes · 2018 · PMC5905845 · PMID 29695924

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did not reach statistical significanceno p-value reported

There was a 14% reduction in the risk of CV events for canagliflozin versus placebo (3-point MACE, 26.9 vs 31.5 participants per 1000 patient-years; HR 0.86; 95% CI: 0.75–0.97; p = 0.02 for superiority); however, the effects of the individual MACE components did not reach statistical significance.

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