Mitochondrial function in individuals at clinical high risk for psychosis.

In schizophrenia, two studies have reported a positive association between the observed increase in complex I function and severity of positive symptoms 19 , 41 ; however, consistent with our results, a negative trend level association was reported between complex I function and negative symptoms 19 .

also in 4,201 other papers

These results are in line with previous studies reporting a positive correlation between elevated lactate levels and neuropsychological symptoms in patients with mitochondrial diseases 43 , including a positive trend level association between in vivo brain 1 H-MRS lactate levels and negative symptoms in schizophrenia 24 .

also in 11,005 other papers