Mutation hotspots at CTCF binding sites coupled to chromosomal instability in gastrointestinal cancers.

Nat Commun · 2018 · PMC5906695 · PMID 29670109

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nominally significantno p-value reported

Out of the four CBS hotspots we examined, three of them were associated with nominally significant expression changes of neighboring genes ( CENPQ , KCNQ5 , and SPG20 ), and these associations were validated in an independent tumor cohort.

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