Dynamic Network Analysis Reveals Altered Temporal Variability in Brain Regions after Stroke: A Longitudinal Resting-State fMRI Study.

Specifically, from the acute stage to the early chronic stage, the temporal variability in the ipsilesional PreCG and the contralesional hippocampus was increased first and then decreased, while the temporal variability of the other regions showed a trend of gradual increase.

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These studies showed that the stroke group exhibited an increasing trend in the low-frequency fluctuations at the acute stage (<7 days after stroke onset) and a decreasing trend from the acute stage to the early chronic stage, which may have been due to an inhibitory deficit from impaired the “task-positive” regions [ 23 – 25 ].

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