Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo.

Cell Rep · 2018 · PMC5908249 · PMID 29617651

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showed a trendno p-value reported

Conversely, 4,313 of 4,986 regions (86.5%) of the genome that lost DNA methylation in early-passage Dnmt3a KO HSCs (hypo-DMRs) showed a trend toward continued loss of methylation in later stage transplant Dnmt3a KO HSCs.

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