Engineering in-vitro stem cell-based vascularized bone models for drug screening and predictive toxicology.

Although a positive trend can be identified in the use of a 1:1 ratio, the results are also heterogeneous and an ideal ratio cannot be defined a priori [ 230 ].

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However, due to the heterogeneity of the experimental parameters used in coculture studies, a clear trend is difficult to establish.

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