MiR-21 over-expression and Programmed Cell Death 4 down-regulation features malignant pleural mesothelioma.

Oncotarget · 2018 · PMC5915117 · PMID 29707109

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Moreover, PDCD4 expression in MPM showed a trend from epithelioid to biphasic and sarcomatoid subtypes, suggesting a role in tumor progression and, more specifically, in epithelial-mesenchymal transition (EMT).

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