The secondary prevention of stroke according to cytochrome P450 2C19 genotype in patients with acute large-artery atherosclerosis stroke.

Oncotarget · 2018 · PMC5915151 · PMID 29707143

Europe PMC DOI

hedged sentence

0.2600

closest p · 5.2× alpha

0.2600

boldest claim

The sentences

did not reach statistical significanceP = 0.26not close (p > 0.1)

However, in the subgroup analysis of the stroke patients who entered CAPRIE trial, the effect of clopidogrel was smaller, and did not reach statistical significance (the annual rate of stroke, MI, and vascular death was 7.15% in clopidogrel group vs. 7.71% in aspirin group; 95% CI, 5.7% to 18.7%; P = 0.26).

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