Propofol induces nuclear localization of Nrf2 under conditions of oxidative stress in cardiac H9c2 cells.

The Nrf2 level in total lysates of H9c2 cells was higher in cells pretreated with 100 μM propofol for 30 min and then incubated with 250 μM H 2 O 2 than in cells treated with only 250 μM H 2 O 2 ( Fig 2D and 2E , S1C and S1D Fig ), although the difference did not reach statistical significance.

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