Metabolism and hydrophilicity of the polarised 'Janus face' all-<i>cis</i> tetrafluorocyclohexyl ring, a candidate motif for drug discovery.

Chem Sci · 2018 · PMC5916015 · PMID 29732086

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The sentences

a clear trendno p-value reported

There is a clear trend that selective fluorinations around the ring increases the polarity of the cyclohexane.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Metabolism and hydrophilicity of the polarised 'Janus face' all-&lt;i&gt;cis&lt;/i&gt; tetrafluorocyclohexyl ring, a candidate motif for drug discovery.

The sentences

Metabolism and hydrophilicity of the polarised 'Janus face' all-<i>cis</i> tetrafluorocyclohexyl ring, a candidate motif for drug discovery.