Barely Significant
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Multi-drug combination therapy with vincristine-melphalan-cyclophosphamide-prednisolone was more effective than cyclophosphamide-prednisolone in stage III myeloma. The Nagoya Myeloma Cooperative Study Group.

Jpn J Cancer Res · 1990 · PMC5918012 · PMID 2126002

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only marginally significantno p-value reported
When the whole group of patients was evaluated, the choice of chemotherapy (VMCP or CP) was not a significant prognostic factor associated with response or survival by uni‐ or multivariate analysis, and the difference between the survival curves of the treatment groups was only marginally significant.

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