Repurposing drugs in oncology (ReDO)-selective PDE5 inhibitors as anti-cancer agents.

Ecancermedicalscience · 2018 · PMC5931815 · PMID 29743944

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showed a trendno p-value reported

The same group also showed that female C57BL/6 mice bearing syngeneic Panc02 pancreatic tumours and treated with sildenafil in drinking water (20 mg/kg/day) had increased survival compared to untreated mice ( P < 0.01), however male mice showed a trend towards decreased survival [ 36 ].

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