GAA•TTC repeat expansion in human cells is mediated by mismatch repair complex MutLγ and depends upon the endonuclease domain in MLH3 isoform one.

Nucleic Acids Res · 2018 · PMC5934671 · PMID 29529236

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did not reach statistical significanceno p-value reported

By contrast, PMS2 knockdown samples reveal a trend towards greater expansion (PMS2sh) that did not reach statistical significance.

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