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Dissemination of <i>Orientia tsutsugamushi</i>, a Causative Agent of Scrub Typhus, and Immunological Responses in the Humanized DRAGA Mouse.

Front Immunol · 2018 · PMC5936984 · PMID 29760694

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Percentage of human CD3 + T cells more than doubled 8 weeks post initial immunization and this was accompanied with a significant increase of CD4 + T cells (~3-fold) and moderate increase for cytotoxic CD8 + T cells (~2-fold), although it did not reach statistical significance (Figures 5 C–E).

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