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One-Week Exposure to a Free-Choice High-Fat High-Sugar Diet Does Not Interfere With the Lipopolysaccharide-Induced Acute Phase Response in the Hypothalamus of Male Rats.

Front Endocrinol (Lausanne) · 2018 · PMC5937016 · PMID 29760677

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The previously observed increase in hypothalamic Il6 mRNA expression did not reach statistical significance due to the experimental set up which was focused on interaction effects between diet and LPS and did not include post hoc analysis between chow/control and diet/control groups.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.