Barely Significant
← all excerpts

Effect of 12 weeks of once-daily tiotropium/olodaterol on exercise endurance during constant work-rate cycling and endurance shuttle walking in chronic obstructive pulmonary disease.

Ther Adv Respir Dis · 2018 · PMC5937154 · PMID 29439648

Europe PMCDOI
1
hedged sentence
0.0004
closest p · 0.0× alpha
0.0004
boldest claim

The sentences

nominally significantp = 0.0004actually significant
However, several lines of evidence point to an effect of the lower dose on exercise endurance: (i) tiotropium/olodaterol 2.5/5 μg significantly improved EET during CWRCE compared with placebo in both MORACTO ® studies [26.5% ( p < 0.0001) and 12.1% ( p = 0.0003)]; (ii) there was a nominally significant improvement in EET during CWRCE after 6 weeks (22.1%, nominal p = 0.0004) in the present study; (iii) in post hoc analysis, change from baseline in EET during CWRCE after 6 and 12 weeks was nominally significant.

also in 7,732 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.