Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells.

After 5 days of treatment, qRT-PCR analysis revealed that co-treatment with FGF8 and BIO upregulated EN1 expression more than treatment with BIO alone, but the increment did not reach statistical significance (Fig. 3c ).

also in 111,027 other papers