Barely Significant
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Potential of quantitative SEPT9 and SHOX2 methylation in plasmatic circulating cell-free DNA as auxiliary staging parameter in colorectal cancer: a prospective observational cohort study.

Br J Cancer · 2018 · PMC5943265 · PMID 29610456

Europe PMCDOI
1
hedged sentence
0.0890
closest p · 1.8× alpha
0.0890
boldest claim

The sentences

showed a trendP = 0.089so close (0.05 < p ≤ 0.1)
Post-therapeutic SHOX2 and SEPT9 ccfDNA methylation in matched samples from individual patients, however, showed a trend towards decreased levels in 70 patients with localised (M 0 , SEPT9 : P = 0.089, SHOX2 : P = 0.13) disease and no decrease in 9 patients with distant metastases (M 1 , SEPT9 : P = 0.67, SHOX2 : P = 0.52) (Fig. 4 ).

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