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Design, Synthesis and Cytotoxic Evaluation of Novel Chalcone Derivatives Bearing Triazolo[4,3-a]-quinoxaline Moieties as Potent Anticancer Agents with Dual EGFR Kinase and Tubulin Polymerization Inhibitory Effects.

Molecules · 2017 · PMC5943945 · PMID 29280968

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quite significantno p-value reported
Chalcone derivatives with diverse chemical architectures are quite significant in anticancer drug discovery and hence are in the center of attention of drug hunters [ 42 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.