Prolonged cenicriviroc therapy reduces hepatic fibrosis despite steatohepatitis in a diet-induced mouse model of nonalcoholic steatohepatitis.

1 C, left column); however, surprisingly, there was a significant decrease in the histologic fibrosis scores of mice treated with high‐dose CVC compared with CDAHFD alone and a strong trend toward reduced fibrosis compared with vehicle controls ( P = 0.10) after 14 weeks of therapy (Fig. 1 C, right column).

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