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Downregulation of Leucine-Rich Repeat-Containing 8A Limits Proliferation and Increases Sensitivity of Glioblastoma to Temozolomide and Carmustine.

Front Oncol · 2018 · PMC5949383 · PMID 29868469

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a strong trendno p-value reported
When we combined the LRRC8A siRNA with chemotherapeutics, our assays again showed a strong trend for additivity in the toxic effects of both treatments, and were far superior to the chemotherapeutics alone.

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