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Diuretics: again the first step in the treatment of most patients with hypertension.

Curr Control Trials Cardiovasc Med · 2001 · PMC59527 · PMID 11806804

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showed a trendno p-value reported
Patients treated with diltiazem had a lower incidence of stroke (RR 0.80, 95% CI 0.65–0.99) whilst patients on an old treatment strategy showed a trend towards a lower incidence of myocardial infarction (RR 1.16, 95% CI 0.94–1.44).

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