Survivin knockdown induces senescence in TTF‑1-expressing, KRAS-mutant lung adenocarcinomas.

Moreover, AT therapy further reduced the size and weight of the tumor nodules derived from BIRC5 siRNA-transfected cells, although the effects of the therapy did not reach statistical significance (when comparing the BIRC5 siRNA group to the triple combination treatment group) ( Fig. 6A–C ).

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