Influence of Gestational Age at Initiation of Antihypertensive Therapy: Secondary Analysis of CHIPS Trial Data (Control of Hypertension in Pregnancy Study).

7 However, what has not been highlighted is that in tight (versus less-tight) control, there was also a nonsignificant trend of similar magnitude toward a decrease in preterm birth (153, 31.5% versus 175, 35.6%, respectively; adjusted OR, 0.85 [0.64–1.11]; P =0.18).

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A similar pattern was seen for delivery at <34 weeks, but the results did not reach statistical significance ( P interaction =0.567; Table 1 overall; Table S5 for chronic and gestational hypertension subgroups).

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