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The IL-4/STAT6/PPARγ signaling axis is driving the expansion of the RXR heterodimer cistrome, providing complex ligand responsiveness in macrophages.

Nucleic Acids Res · 2018 · PMC5961189 · PMID 29506156

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showed a trendno p-value reported
The repressive effects of the ligands were not significant on the regulatory regions near repressed genes, but they showed a trend towards repressed RNAPII-pS2 binding (Figure 6B and Supplementary Figure S6A ).

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