Barely Significant
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Debate: The potential role of estrogen in the prevention of heart disease in women after menopause.

Curr Control Trials Cardiovasc Med · 2000 · PMC59620 · PMID 11714428

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a significant trendno p-value reported
HRT was associated with more secondary cardiac events as compared to placebo during year 1 of treatment, and with a significant trend toward fewer events in years 4 and 5.

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