Plasma Cell Alloantigen 1 and IL-10 Secretion Define Two Distinct Peritoneal B1a B Cell Subsets With Opposite Functions, PC1^high Cells Being Protective and PC1^low Cells Harmful for the Growing Fetus.

Treg frequencies were significantly reduced in decidual tissue and Treg cell numbers were significantly diminished in spleens from NP female recipients of PC1 low cells (Figure 4 C; Figure S2D in Supplementary Material), while changes in the splenic Treg frequencies did not reach statistical significance (Figure 4 E).

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