highly significantp = 0.006
In multivariate Cox proportional hazard regression analysis with adjustment for cardiovascular risk factors we found this difference to be highly significant ( p = 0.006).
In multivariate Cox proportional hazard regression analysis with adjustment for cardiovascular risk factors we found this difference to be highly significant ( p = 0.006).
Moreover, PEAR1 rs12566888 minor allele carriers also showed an increased risk in all patients (hazard ratio, 1.69; 95% confidence interval, 0.87–3.27, p = 0.122), which was marginally significant in male patients (hazard ratio, 2.12; 95% confidence interval, 1.02–4.43, p = 0.045; n = 425).
Multivariate Cox proportional hazard analysis showed a significant association of this SNP with myocardial infarction ( p = 0.013; Wald test) and a borderline significant association of rs2768759 and all-cause mortality ( p = 0.051; Wald test).
Moreover, there was a strong trend toward lower ADP induced aggregation in male minor allele carriers of rs41273215.