Barely Significant
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Frailty in Older Adults Is Associated With Plasma Concentrations of Inflammatory Mediators but Not With Lymphocyte Subpopulations.

Front Immunol · 2018 · PMC5964167 · PMID 29868017

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a clear trendno p-value reported
These values were always located above the reference range, showing a clear trend to increase with frailty status.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.