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CPR-IR is an insulin resistance index that is minimally affected by hepatic insulin clearance-A preliminary research.

PLoS One · 2018 · PMC5965889 · PMID 29791512

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showed a trendno p-value reported
The decrease of HIC showed a trend for association with a risk of incident metabolic syndrome [ 28 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.