Of note, the average percentages of increased IFN-γ- or decreased IL-17A-producing CD4 + T cells resulted from deletion of CXCR3 that expressed PD-1 also increased, although the difference did not reach statistical significance (Figure S5B in Supplementary Material).
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The CXC Chemokine Receptor 3 Inhibits Autoimmune Cholangitis <i>via</i> CD8<sup>+</sup> T Cells but Promotes Colitis <i>via</i> CD4<sup>+</sup> T Cells.
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