Specific synbiotics in early life protect against diet-induced obesity in adult mice.

Diabetes Obes Metab · 2018 · PMC5969090 · PMID 29460474

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0.0670

closest p · 1.3× alpha

0.0670

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The sentences

showed a trendP = .067so close (0.05 < p ≤ 0.1)

3.2 Early life synbiotics improve glucose and lipid metabolism in adulthood To address whether protection from obesity was also associated with improved metabolic parameters, we determined the HOMA‐IR index as a surrogate marker for insulin resistance and found that the SYN group showed a trend towards reduced HOMA‐IR ( P = .067) compared with the CTRL group (Figure 2 A), suggesting improved insulin sensitivity.

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