Consequently, there is an important trend toward the adoption of 3D cell culture systems 22 , 30 , 31 that is driving the need for new imaging approaches that can support volumetric imaging of microscale spatial variations in ECM mechanics across time.
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Photonic force optical coherence elastography for three-dimensional mechanical microscopy.
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The data were ordered such that a z C > 0 indicates an increasing trend while a z C < 0 indicates a decreasing trend.