ASCEND: A Study of Cardiovascular Events iN Diabetes: Characteristics of a randomized trial of aspirin and of omega-3 fatty acid supplementation in 15,480 people with diabetes.

16 Similarly, in a trial of omega-3 FA (1 g daily) among 11,000 patients who had survived a myocardial infarction, there was a 13% (95% CI, 1–24%) proportional reduction in coronary events but, both this and the 10% (95% CI, 1–18%) reduction in the primary outcome of cardiovascular events, were only marginally significant. 17 As a consequence, several large randomized trials (including the present ASCEND trial) were started in order to generate more reliable evidence about the effects of omega-3 FA supplementation.

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