Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

Nat Genet · 2017 · PMC5972004 · PMID 28135244

Europe PMC DOI

hedged sentences

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closest p · 0.2× alpha

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boldest claim

The sentences

nominally significantP < 0.01actually significant

Most SNVs also show association with hypertension in the UK Biobank data, for example 93 of the 107 validated sentinel SNVs are nominally significant ( P < 0.01) ( Supplementary Table 7 ).

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highly significantno p-value reported

Sentinel variants in three genes which were highly significant in the combined meta-analysis ( Tables 2 and 3 ) are selected for experimental testing and were successfully genotyped, each for at least 100 samples.

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